LEONARDO BRAINMAP EEG and PSG Software

LEONARDO BRAINMAP advanced Features:

Clinical and Research EEG, PSG and LTM Data Acquisition and Analysis Software for Linux/Ubuntu, MAC and MS Windows XP/Vista 32 and 64 bits.

The LEONARDO BRAINMAP has rs232 data interface for external medical products and ist able to record its traces in EDF data format:

LEONARDO BRAINMAP EEG and PSG

LEONARDO BRAINMAP is the PC software that brings everything together! 25 years of dedication to the field of neurodiagnostics has allowed to develop a software platform that is easy to use, yet flexible enough to expand upon.

LEONARDO EEG and PSG is a state-of-the-art, very high-performance up to 256-channel EEG and PSG Recording based on notebook or PC System and provides clear, sharp traces. The amplifier system is designed specifically for the EEG and PSG monitoring to satisfy the needs of the physician's office, hospital, or medical center and combines the latest digital design techniques with years of amplifier design and manufacturing experience.

LEONARDO has continued to evolve and improve through ongoing research and development. The default detection parameters are optimized for minimal false positive and false negative results, however the user can adjust parameters as needed.

During data review, the LEONARDO EEG shows marks to indicate patient pushbutton events and automatic detections. Clicking on these marks will bring up the corresponding page of EEG data for visual confirmation. It is also used for marking events of interest for saving, both EEG and digital video.

LEONARDO is no compromise on quality or reliability. Each channel is completely software configurable with independent control of gain, filters, resolution and scan rate.

LEONARDO export functions: Export allow output of information (raw data, graphics, and text) to standard formats (including ASCII, AVI and EDF), as well as direct links to programs f.e. in OpenOffice for report generation and database management.

Archive Manager: Archive Manager allows easy archiving of the studies to different types of media, such as CD or DVD.

Reviewer: Easily bring up a patient study for quick review with intuitive database. Utilize keyboard or on-screen controls to navigate through a record. Amplitude and measurement tools, along with zoom capabilities allow the user to accurately analyze specific waveforms. Potential and Waves Mapping and Spectral Analysis tools are included for advanced data review. Built-in network compatibility provides instant access to data, as well as real-time monitoring of on going studies.

Easy Setup: With LEONARDO's simplified installation package, utilize the pre-defined list of annotations, keyboard events, photic stimulation routines, duration events, or montages to set up the system quickly.

User Profiles: Use User Profile to configure a profile for each technician or doctor using the system. Their montage, trace color, record configuration, review setup, and other preferences are stored and loaded at any time.

Recorder: The recording module opens instantly, with just a double-click on the "start-up" icon. Easily perform impedance checks, calibrations, and montage adjustments. Entering user-defined events and annotations is as simple as a single keystroke. Accurate, high-quality digital recording is guaranteed.

Remontages: Create virtually remontages, off-line or in real-time, with the remontage editor. The remontage editor uses a graphical head-stamp interface for programming scalp montages, plus an invasive electrode remontage creator. User-defined average-reference remontages, channel types, and trace colors can also be defined. The remontages used for a given study are also stored with the EEG data for retrieval during review or in the future when reviewing archived data.

Advanced Features:

  • Review patient data anywhere
  • Friendly, easy-to-use interface
  • Ideal for sharing data with colleagues
  • Remontage, Spectral Analysis, CSA-analysis
  • Brain Mapping for EEG and PSG
  • Friendly, easy-to-use software
  • Automated EEG and PSG events analysis
  • Digital video/audio capabilities, cut video editor
  • Attractive, custom configurable EEG and PSG reports

The amplifier system

The amplifier system provides for patient safety optical isolation, signal conditioning (physiological signal amplification and filtering), and digitization. Communications with a host computer are accomplished using WLAN, LAN, RS232 or USB protocol over CAT5 cable. A host computer sets the sample rate, starts and stops the data transmission, monitors the digital data, and stores it to hard disk.

L24L59poly

The latest high-performance Pentium-based PC with one or two high resolution monitors are network ready.

Long term monitoring

LEONARDO EEG and PSG offers the most flexible configurations to suit the needs of your lab. This multi-functional software permits recording and analysis of routine EEG and PSG studies as well as long-term epilepsy monitoring. LEONARDO is the universal software used in clinical systems.

Seizure and spike analysis:

LEONARDO EEG is an on-line seizure and spike analysis software. LEONARDO utility is proven to reduce review time of long-term EEG recordings, allowing the person reading the EEG study to quickly view events of interest without having to page through the entire recording.

CSA -analysis:

CSA Analysis

Polysomnography:

PSG Recording and Analysis: Fully-Automated Sleep Stager is an analysis module in LEONARDO PSG software, that identifies standard Rechtschaffen and Kales sleep stages automatically, deriving information from various parameters of the EEG, EOG, and Chin EMG. FASS is extremely accurate and easy to use. With LEONARDO, a sleep study is completely staged in less than one minute, providing a great time savings to the sleep lab.

The software comes with powerful algorithms for analyzing and auto-scoring sleep records. Featuring automated respiratory event, desaturation, snore, and PLM detection, display and reporting of CPAP/BiLevel treatment, heart rate, oximetry and other DC trends. The Sleep Report Wizard processes the staging, latencies, graphical trends and parametric breakdowns for easy analysis and comparisons. Customized reports can be created.

During an overnight sleep study, the patient's brain waves and other vital signs are monitored on a recording system. Eight hours of recordings are typically done and saved on the computer hard drive, the equivalent of a several hundred page printed record. It is then the job of the sleep technician to review these records in detail in order to evaluate the sleep quality of the patient so that the physician can ultimately make a diagnosis. The "review process" can take up to two or three hours for a patient with a disorder.

With LEONARDO PSG, part of the review process is automated such that the total time for the technician is significantly reduced. This obviously is of benefit to the sleep disorders center or hospital in their constant pursuit of cost containment.

LEONARDO PSG uses a rule-based approach to sleep staging, which combines automatically-detected sleep events (spindles, phasic REM, etc.) with automatically-computed parameters (FFT frequency analysis, Event Recognition, amplitude, etc.), to replicate Rechtschaffen and Kales sleep staging. LEONARDO provides full staging of wakefulness and all 5 stages of sleep.

Two levels of analysis are performed: individual page analysis (First Pass), and context and stage transition analysis (Second Pass). During the First Pass, LEONARDO assigns a sleep stage to each page. The stage is determined based on a decision flow chart that takes into account the presence/absence of sleep events and the values of the computed parameters on that page. During the Second Pass, LEONARDO applies context rules (3 minute rule for Stage 2, REM continue rule, etc.) and stage transition rules (REM-to-Wake, Stage 1-to-Wake, etc.).

The comprehensive user interface of LEONARDO permits changing some of the staging parameter thresholds and rules, as well as default settings. Amplitude and EEG frequency trends, such as Delta and Alpha percentage trends and Chin EMG amplitude trends, are also computed and can be displayed on the PSG timeline along with the sleep staging hypnogram.

LEONARDO creates a fully-staged study that can be reviewed, modified, and exported to a standard report. The study results can be compared to an expert PSG scorer’s staging.

PSG curves:

PSG curves

Sleep analysis and staging:

Sleep Analysis

EDF data format

LEONARDO accepts EEG file in standard EDF format and creates sequence of topographic maps. Individual topographic maps could be copied in Clipboard for future examination or publishing.

VIDEO BRAINMAP

Any LEONARDO-based study, along with its synchronized digital video/audio, may be transported on a CD or DVD. Then, using the disk in a Windows XP-based PC, review that study and digital video/audio. Physicians and hospitals can send data acquired in their laboratory to others for review, facilitating exchange of data with referring physicians, colleagues, collaborators, and/or to obtain a second opinion.

Panorama digital video/audio options are available:

EEG curve and Video

EEG Brain Mapping and Activity Localization in LEONARDO

EEG brain mapping:

EEG brain mapping

EEG brain mapping:

EEG brain mapping

Sleep period EEG brain mapping:

Sleep period EEG brain mapping

EP brain mapping:

EP brain mapping

EP in LEONARDO EEG and PSG

Adwanced Features:

  • Open source EEG and EP recording software for Linux in EDF data format is available
  • Photic and Sound Stimulators available
  • Free defineable stimulation programs
  • Exactly synchronized (1 msec) RS-232 for external stimulation PC
  • One or two Patient joysticks. X and Y axis behavior and push of buttons will be recorded
  • Brain mapping and Localization Software

MINI LED Photic Stimulator:

USB Photic

Localization of pathological electrical brain activity sources

Functions:

  • localization of pathological electrical activity sources when suffering from epilepsy, injuries, insults, neoformations
  • localization of evoked potentials sources, wave patterns, rhythmic activity generators

Methods of Data Editing:

  • selection of the arbitrary fragment of the recorded EEG/EP for the detailed analysis
  • removal of the channels with the artifacts
  • correction of the electrode names and settings
  • capability of the recorded EEG/EP inversion
  • isoline correction of the whole file or specified interval (for example, basing on the prestimulative EP interval)
  • signal resampling
  • signal filtering in the standard ranges or arbitrary frequency band
  • calculating of the power spectrum of the whole record (or its part) for the detection of the power spectral components sources

Models Applied for Data Analysis:

  • model with non-stationary dipoles
  • model with stationary dipoles

Models with Non-stationary Dipoles:

  • for every time point of the analyzed data its own dipole model is calculated which includes one or two non-stationary dipoles
  • it is possible to specify the averaging window according to time when calculating the dipole sources

Model with Stationary Dipoles:

single model with the given number of dipoles (from one to eight) for the whole data fragment is calculated; model variants:

  • dipole centers are linked with the given structures
  • search of the optimal arrangement of the dipole centers in the brain volume
  • search of the steady optimal dipole orientation for the whole data fragment

Visualization of Calculated Dipole Sources:

  • on three head views
  • on diagrammatic sectional views of the brain structures
  • on tomographic brain images (MRT-images)
  • validity assessment of the calculated parameters and the automatic selection of the reliable sources
  • displaying the total information about the dipole model parameters
  • mapping of the dipole ratio distribution on the axial sections
  • simultaneous review of the several files in the multiwindowing

Amplitude Mapping of:

  • EEG and EP on the head surface
  • EEG and EP calculated on the cortex surface
  • dipole model potentials and rest potentials

Graphs Displaying of:

  • EEG and EP traces
  • dipole model potentials and rest potentials
  • dipole moment projections on the coordinates and the dipole moment modules

Data Input:

  • EEG and EP data file reading recorded in different binary and ASCII formats, the European data format (EDF) supporting
  • MRT and CT brain images input, recorded on the different types of tomographes

Additional Capabilities:

  • creation of EEG and EP test files with the given dipole model for the examination of the direct and inverse tasks solving
The program got the research results verification in the leading medical research institutes and clinics: N.N. Burdenko Institute of Neurosurgery, Institute of Neurology, I.M. Sechenov Moscow Medical Academy, N.V. Skliphosovsky Ambulance Research Center, Moscow Research Institute of Psychiatry of the Ministry of Health of the Russian Federation, Institute for Neurosurgical Research Named after A.L. Polenov, and etc.

Localization Dipoles:

BrainLoc1

Slices view:

BrainLoc2

Localization deviation:

BrainLoc3

Localization and MRI:

BrainLoc4